Chemistry 4320/5320

Spectroscopic Identification of Organic Compounds

Instructor: Dr. Dan Swartling Office: FH 102 (105, 301) Phone: 3431

Purpose: This course is intended to introduce the student to the spectroscopic methods used in the determination of organic structures. Examples of commonly used techniques include infrared, raman, nuclear magnetic resonance, ultraviolet, x-ray and mass spectroscopy.

The student is expected to be able to explain qualitatively the theory behind each technique used and to correlate the relationships between atomic and molecular properties and their effect on spectra. The student should be able to interpret IR, NMR, and mass spectral data, and become familiar with the basic operation of IR and NMR instruments.

Text: Introduction to Spectroscopy, 3rd edition – Pavia, Lampman and Kriz

Topics: (in approximate order)

·  Overview

·  Mass Spectrometry

·  Infrared Spectroscopy

·  1H NMR Spectrometry

·  13C NMR Spectrometry

·  Heteroatomic NMR Spectrometry

·  Advanced 1D and 2D NMR techniques (APT, DEPT, COSY, NOESY, HETCOR)

Tests: There will be four exams covering specific topics and a final exam. All tests will consist of two parts - an in-class exam and a take home problem set. For the take-home portion of the exam the student may use any books and notes that they wish.

Laboratory: The laboratory will primarily entail the identification of unknown organic compounds. Individual samples will be provided weekly along with supplementary data such as mass spectra or elemental analysis. The student will be responsible for both sample preparation and running spectra. In addition the laboratory may include 1-3 specific experiments designed to illustrate other aspects of spectroscopic analysis.

CHEM 5320 (graduate) students will be expected to do additional assignments which may be of the following: One additional experiment involving a separation technique, an oral presentation describing a recent paper that illustrates the use of NMR techniques, and occasional extra problem assignments.

Grading: Lab 35%, Problems 10%, Tests 35%, Final 20%

Chem 432/532 Booklist