Figure 1. If we put
human red blood cells (RBCs) in a solution having the same water
concentration as the inside of the cell (an isotonic solution), the cells look like this. They have
smooth surfaces and are thinner in their centers than on their edges. These are
normal red blood cells and is how they look when they are in our blood
vessels. Water is moving into and out of these cells at the same rate. With
no net change in water volume, the cells retain their normal shapes.
Figure
2. The cells in this picture have been left in a solution of lower water
concentration (higher dissolved solids, hypertonic), and the net movement of water was out of the cells,
from the area of higher water concentration (inside the cells) to the area of
lower water concentration (outside the cells). This has caused the cells to
deflate and their cell membranes to wrinkle.
The magnification here is a little lower and the lighting is a little
different; however, the important difference to notice is the shape of the
membranes. As the cells lost water by osmosis their membranes wrinkled, sort of
the way a mylar balloon wrinkles as it loses air.

Figure
3. These are normal onion cells. Each is bounded by a darkly stained cell
wall. Just inside the cell wall is a cell membrane, pressed up against the wall,
like an inner tube in a tire. (The cell membrane is too thin to see at this
magnification.) You can see nuclei (light blue) in some cells. The rest of the
material in the cell is called cytoplasm. The cells look like this when
they are in distilled water or in a water solution where the water concentration
matches that in the cell.
Figure
4. If we change the solution around the cells to one that has a lower water
concentration (higher in dissolved solids), the net movement of water will be
out of the cell, by osmosis. As it loses water, the cytoplasm will shrink and
the cell membrane will follow it, being pulled away from the cell wall. With
less water in the cytoplasm to support them, the cells lose their shape -- they
shorten, thicken, and lose rigidity. This onion has become shriveled, soft, and pliable
-- dehydrated.