Scott H. Northrup

                                       CURRICULUM VITAE

 

Address

 

Office:       Tennessee Technological University

Department of Chemistry, Box Number 5055

Cookeville, TN 38505

Phone: (931) 372-3748

 

Home:      628 Rice Circle

Cookeville, Tennessee 38501

Phone: (931) 528-6291

 

Internet:   snorthrup@tntech.edu

 

 

Area of Specialization

 

      Computational Chemistry, Molecular Modeling of Proteins and Nucleic Acids.

 

Education

 

Ph.D. in physical chemistry, University of Colorado in Boulder, 1979. Theoretical Studies of Reaction Dynamics in Solution with Research Supervisor Professor James T. Hynes.

 

M.S. in Chemistry, University of Colorado in Boulder, 1976.

 

B.A. in Chemistry, University of Northern Colorado, 1973.

 

 

Experience

 

University of Colorado: Teaching Assistant, 1973-74, 1975-76; Research Assistant, 1974-78.

University of Houston: Visiting Assistant Professor of Chemistry, 1978-79;

University of Houston: Robert A. Welch Foundation Postdoctoral Fellow, 1979-80, with Research Supervisor Professor J. Andrew McCammon.

Tennessee Technological University: Assistant Professor of Chemistry, September, 1980 - 1983; Associate Professor of Chemistry, September, 1983 - August, 1988; Full Professor of Chemistry, September, 1988 - present.

Tennessee Technological University: Chair, Department of Chemistry, August, 1997 ≠ July, 2005.

 

 

 

Professional Societies

 

American Chemical Society

American Scientific Affiliation

Biophysical Society

Sigma Xi Scientific Research Society

 

 

Awards

 

Recipient of Camille and Henry Dreyfus Scholar/Fellow Award; November, 1990.

Caplenor Faculty Research Award for outstanding faculty research accomplishments at Tennessee Technological University; 1988.

Sigma Xi Research Award for outstanding contribution at TTU; 1982, 1987.

Recipient of NIH Research Career Development Award; 1985-90.

Awarded NIH Postdoctoral Fellowship, National Research Service Award; 1979.

Robert A. Welch Foundation Postdoctoral Fellow; 1979-80.

Theodore S. Gilman Award for Outstanding Teaching Fellow in Chemistry, University of Colorado; 1973-74.

Outstanding Senior Chemistry Student, University of N. Colorado; 1972-73.

 

 

Funded Projects

 

ACS Petroleum Research Fund grant Type B, Simulation of Electron Transfer in Metalloproteins, $25,000; September, 1995 - August, 1997.

NIH/NIMH grant, Prediction and Display of Interactions of Macromolecules, Small Business Innovation Research, $500,000; September, 1993 - August, 1995. (with Consultec Scientific Inc., Knoxville, TN)

NIH/NIGMS grant, Protein-Protein and Protein-DNA Association in Solution, $300,000; April, 1990 - March, 1995.

ACS Petroleum Research Fund grant Type B, Dynamics of DNA-Protein Association, $20,000; September, 1991 - August, 1993.

Camille and Henry Dreyfus Scholar/Fellow Award, Brownian Dynamics of Nonspecific Binding of Genome Regulatory Proteins to DNA, $65,000; November, 1990 - November, 1993.

NIH/NLM grant, Prediction and Display of Interactions of Macromolecules, Small Business Innovation Research, $50,000; October, 1990 - April, 1991. (with Consultec Scientific Inc., Knoxville, TN)

ACS Petroleum Research Fund grant Type B, Brownian Dynamics of Biomolecular Reactions, $20,000; June, 1988 - August, 1990.

NIH/NIGMS research grant, Computational Studies of Protein Association in Solution, $120,000; April, 1988 - March, 1991.

NIH Research Career Development Award, Computational Studies of Protein Association in Solution, $259,545; June, 1985 - May, 1990. (5 years full release time)

ACS Petroleum Research Fund grant Type B, Brownian Dynamics of Diffusion Influenced Macromolecular Reactions, $15,000; June, 1985 - August, 1988.

NIH/NIGMS grant, Computational Studies of Ligand Binding to Enzymes, $43,000; September, 1985 - August, 1987.

Research Corporation grant for Dynamical Cooperativity in Helix-Coil Transitions, $5,000; 1981 - 1983.

American Chemical Society, Petroleum Research Fund Type G grant for Structure and Dynamics of Lipid Bilayers, $10,000; 1981 - 1983.

NIH Postdoctoral Fellowship, National Research Service Award, $13,800; 1979.

 

 

Publications

 

1.   Northrup, S. H. and J. T. Hynes, Coupling of Translational and Reactive Dynamics for a Simple Lattice Model, J. Stat. Phys., 18, p. 91-105, 1978.

 

2.   Northrup, S. H. and J. T. Hynes, Coupling of Translational and Reactive Dynamics for a Fokker-Planck Model, J. Chem. Phys., 68, p. 3203-3216, 1978.

 

3.   Northrup, S. H. and J. T. Hynes, On the Description of Reactions in Solution, Chem. Phys. Lett., 54, p. 244-247, 1978.

 

4.   Northrup, S. H. and J. T. Hynes, On Reaction Rate Constants and Kernels, Chem. Phys. Lett., 54, p. 248-252, 1978.

 

5.   Northrup, S. H. and J. T. Hynes, Reactive Dynamics for Diffusive Barrier Crossing, J. Chem. Phys., 69, p. 5246-520, 1978.

 

6.   Northrup, S. H. and J. T. Hynes, Initial Condition Effects for Diffusive Barrier Crossing, J. Chem. Phys., 69, p. 5261-5266, 1978.

 

7.   Northrup, S. H. and J. T. Hynes, Short Range Caging Effects for Reactions in Solution. I. Reaction Rate Constants and Short Range Caging Picture, J. Chem. Phys., 71, p. 871-883, 1979.

 

8.   Northrup, S. H. and J. T. Hynes, Short Range Caging Effects for Reactions in Solution. II. Escape Probability and Time Dependent Reactivity, J. Chem. Phys., 71, p. 884-893, 1979.

 

9.   Northrup, S. H., Theoretical Studies of Reaction Dynamics in Solution, PH.D Thesis, available through Xerox Univ. Microfilms, 300 North Zeeb Road, Ann Arbor, Michigan 48106.

 

10. Northrup, S. H. and J. A. McCammon, Simulation Methods for Protein Structure Fluctuations, Biopolymers, 19, p. 1001-1016, 1980.

 

11. McCammon, J. A., S. H. Northrup, M. Karplus and R. Levy, Helix-coil Transitions in a Simple Polypeptide Model, Biopolymers, 19, p. 2033-2045, 1980.

 

12. Northrup, S. H. and J. A. McCammon, Efficient Trajectory, Simulation Methods for Diffusional Barrier Crossing Processes, J. Chem. Phys., 72, p. 4569-4578, 1980.

 

13. Northrup, S. H. and J. T. Hynes, The Stable States Picture of Chemical Reactions. I. Formulation for Rate Constants and Initial Condition Effects, J. Chem. Phys., 73, p. 2700-2714, 1980.

 

14. Northrup, S. H., M. R. Pear, J. A. McCammon and M. Karplus, Molecular Dynamics of Ferrocytochrome C, Nature, 286, p. 304-305, 1980.

 

15. Pear, M. R., S. H. Northrup, and J. A. McCammon, Diffusional Correlations in Polymer Dynamics, J. Chem. Phys., 73, p. 4703-4704, 1980.

 

16. Pear, M. R., S. H. Northrup, J. A. McCammon, M. Karplus and R. Levy, Correlated Helix-coil Transitions in Polypeptides, Biopolymers, 20, p. 629-632, 1981.

 

17. Northrup, S. H., M. R. Pear, J. A. McCammon, M. Karplus and T. Takano, Internal Mobility of Ferrocytochrome c: Theory and Experiment, Nature, 287, p. 659-660, 1980.

 

18. Northrup, S. H., M. R. Pear, J. D. Morgan, J. A. McCammon and M. Karplus, Molecular Dynamics of Ferrocytochrome c: Equilibrium Results, J. Mol. Biol., 153, p. 1087-1109, 1981.

 

19. Northrup, S. H., M. R. Pear, J. D. Morgan and J. A. McCammon, Molecular Dynamics of Ferrocytochrome c: Fluctuation Anisotropy, Proceedings of Sixth Annual Taniguchi International Symposium of Biophysics, Osaka, Japan, 1980.

 

20. Northrup, S. H., M. R. Pear, Chyuan Lee, J. A. McCammon and M. Karplus, Dynamical Theory of Activated Processes in Globular Proteins, Proc. Natl. Acad. Sci. USA, 79, p. 4035-4039, 1982.

 

21. Mao, B., M. R. Pear, J. A. McCammon and S. H. Northrup, Repulsive Interactions between Polar and Apolar Atoms in Globular Proteins, J. Mol. Biol., 151, p. 199-202, 1981.

 

22. Mao, B., M. R. Pear, J. A. McCammon and S. H. Northrup, Molecular Dynamics of Ferrocytochrome c: Anharmonicity of Atomic Displacements, Biopolymers, 21, p. 1979-1989, 1982.

 

23. McCammon, J. A. and S. H. Northrup, Gated Binding of Ligands to Proteins, Nature, 293, p. 316-317, 1981.

 

24. Northrup, S. H., F. Zarrin and J. A. McCammon, Rate Theory for Gated Diffusion-Influenced Ligand Binding to Proteins, J. Chem. Phys., 86, p. 2314-2321, 1982.

 

25. Szabo, A., D. Shoup, S. H. Northrup and J. A. McCammon, Stochastically Gated Diffusion-Influenced Reactions, J. Chem. Phys., 77, p. 4484-4493, 1982.

 

26. Morgan, J. D., J. A. McCammon and S. H. Northrup, Molecular Dynamics of Ferrocytochrome c: Time Dependence of the Atomic Displacements, Biopolymers, 22, p. 1579-1593, 1983.

 

27. Northrup, S. H. and J. A. McCammon, Saddle-Point Avoidance in Diffusional Reactions, J. Chem. Phys., 78, p. 987-989, 1983.

 

28. McCammon, J. A., C. Y. Lee and S. H. Northrup, Sidechain Rotational Isomerization in Proteins: A Mechanism Involving Gating and Transient Packing Defects, J. Amer. Chem. Soc., 105, p. 2232-2237, 1983.

 

29. Berkowitz, M., J. D. Morgan, J. A. McCammon and S. H. Northrup, Diffusion-Controlled Reactions. A Variational Formula for the Optimum Reaction Coordinate, J. Chem. Phys., 79, p. 5563-5565, 1983.

 

30. Northrup, S. H. and J. A. McCammon, Gated Reactions, J. Amer. Chem. Soc., 106, p. 930, 1984.

 

31. Northrup, S. H., S. A. Allison and J. A. McCammon, Brownian Dynamics Simulation of Diffusion-Influenced Biomolecular Reactions, J. Chem. Phys., 80, p. 1517-1524, 1984.

 

32. Northrup, S. H., Molecular Mechanics of Kink Formation in Lipid Monolayers, J. Phys. Chem., 88, p. 3441-3446, 1984.

 

33. Allison, S. A., N. Srinivasan, J. A. McCammon and S. H. Northrup, Diffusion Controlled Reactions Between a Spherical Target and Dumbell Dimer by Brownian Dynamics Simulation, J. Chem. Phys., 88, p. 6152-6157, 1984.

 

34. Northrup, S. H., Chemistry Through Models, book review, J. Amer. Chem. Soc., 106, p. 7656, 1984.

 

35. Allison, S. A., J. A. McCammon and S. H. Northrup, Dynamics of Macromolecular Interactions, J. Amer. Chem. Soc., Symposium Series #302, 216-231, 1986.

 

36. McCammon, J. A., S. A. Allison and S. H. Northrup, Theoretical Molecular Biology: Some Recent Developments, J. Molecular Science, 3, p. 193-204, 1985, Peopleπs Republic of China.

 

37. McCammon, J. A., S. H. Northrup and S. A. Allison, Diffusional Dynamics of Ligand-Receptor Association, J. Phys. Chem., 90, p. 3901-3905, 1986.

 

38. Allison, S. A., S. H. Northrup and J. A. McCammon, Extended Brownian Dynamics of Diffusion Controlled Reactions, J. Phys. Chem., 83, p. 2894-2899, 1985.

 

39. Allison, S. A., S. H. Northrup and J. A. McCammon, Simulation of Biomolecular Diffusion and Complex Formation, Biophys. J., 49, p. 167-175, 1986.

 

40. Northrup, S. H. and M. S. Curvin, Molecular Dynamics Simulation of Disorder Transitions in Lipid Monolayers, J. Phys. Chem., 89, p. 4707-4713, 1985.

 

41. McCammon, J. A., T. P. Lybrand, S. A. Allison and S. H. Northrup, Ligand Binding: New Theoretical Approaches to Molecular Recognition, Biomolecular Stereodynamics-4th Conversation, 1986, ed. R. H. Sarma, Adenine Press, NY.

 

42. Northrup, S. H., M. Curvin, S. A. Allison and J. A. McCammon, Optimization of Brownian Dynamics Methods for Diffusion-Influenced Rate Constant Calculations, J. Chem. Phys., 84, p. 2196-2203, 1986.

 

43. Northrup, S. H., J. Smith, J. O. Boles and J. C. L. Reynolds, The Effect of Dipole Moment on Diffusion-Controlled Bimolecular Reaction Rates, J. Chem. Phys., 84, p. 5536-5544, 1986.

 

44. Northrup, S. H., J. C. L. Reynolds, C. M. Miller, K. J. Forrest and J. O. Boles, Diffusion Controlled Association Rate of Cytochrome c and Cytochrome c Peroxidase in a Simple Electrostatic Model, J. Amer. Chem. Soc., 108, p. 8162-8170, 1986.

 

45. McCammon, J. A., R. J. Bacquet, S. A. Allison and S. H. Northrup, Trajectory Simulation Studies of Diffusion-Controlled Reactions, Faraday Discussions, 83, p. 213-222, 1987.

 

46. Northrup, S. H., J. O. Boles and J. C. L. Reynolds, Electrostatic Effects in the Brownian Dynamics of Association and Orientation of Heme Proteins, J. Phys. Chem., 91, p. 5991-5998, 1987.

 

47. Northrup, S. H., J. A. Luton, J. O. Boles and J. C. L. Reynolds, Brownian Dynamics Simulation of Protein Association, J. Computer-Aided Molecular Design, 1, p. 291-311, 1988.

 

48. Northrup, S. H., J. O. Boles and J. C. L. Reynolds, Brownian Dynamics of Cytochrome c and Cytochrome c Peroxidase Association, Science, 241, p. 67-70, 1988.

 

49. Northrup, S. H., Diffusion-Controlled Ligand Binding to Multiple Competing Cell-Bound Receptors, J. Phys. Chem., 92, p. 5847-5850, 1988.

 

50. Northrup, S. H. and R. G. Herbert, Brownian Simulation of Cytochrome C551 Association and Electron Self-Exchange, J. Molecular Liquids, 41, p. 207-222, 1989.

 

51. Northrup, S. H., T. G. Wensel, C. F. Meares, J. J. Wendoloski, and J. B. Matthew, Electrostatic Field Around Cytochrome c: Theory and Energy Transfer Experiment, Proc. Nat. Acad. Sci. USA, 87, p. 9503-9507, 1990.

 

52. Reynolds, J. C. L., K. F. Cooke and S. H. Northrup, Electrostatics and Diffusional Dynamics in the Carbonic Anhydrase Active Site Channel, J. Phys. Chem., 94, p. 985-991, 1990.

 

53. Northrup, S. H. and R. G. Herbert, Brownian Simulation of Protein Association and Reaction, J. of Quant. Chem., 17, p. 55-71, 1990.

 

54. Eltis, L. D., R. G. Herbert, P. D. Barker, A. G. Mauk and S. H. Northrup, Reduction of Horse Heart Ferricytochrome c by Bovine Liver Ferrocytochrome b5. Experimental and Theoretical Analysis, Biochemistry, 30, p. 3663-3674, 1991.

 

55. Northrup, S. H., Theoretical Simulation of Protein-Protein Interactions, in Cytochrome c: A Multidisciplinary Approach, University Science Books, Sausalito, CA, eds. R. A. Scott and A. G. Mauk, p. 543-570, 1996.

 

56. Northrup, S. H. and H. P. Erickson, Kinetics of Protein-Protein Association Explained by Brownian Dynamics Computer Simulation, Proc. Nat. Acad. Sci. USA, 89, p. 3338-3342, 1992.

 

57. Andrew, S. M., K. A. Thomasson and S. H. Northrup, Simulation of Electrons Transfer Self-Exchange in Cytochrome c and b5, J. Amer. Chem. Soc., 115, p. 5516-5521, 1993.

 

 

 

58. Northrup, S. H., K. A. Thomasson, C. M. Miller, P. D. Barker, L. D. Eltis, J. G. Guillemette, and A. G. Mauk, Effects of Charged Amino Acid Mutations on the Bimolecular Kinetics of Reduction of Yeast Iso-1-ferricytochrome c by Bovine Ferrocytochrome b, Biochemistry, 32, p. 6613-6623, 1993.

 

59. Northrup, S. H., Hydrodynamic Motions of Larger Molecules, Current Opinion in Structural Biology, 4, p. 269-274, 1994.

 

60. Mauk, A. G., M. R. Mauk, G. R. Moore, and S. H. Northrup, Experimental and Theoretical Analysis of the Interaction Between Cytochrome c and Cytochrome b5, J. Bioenerg. Biomem., 27, p.311-330, 1995.

 

61. Northrup, S. H., Computer Modeling of Protein-Protein Interactions, in Protein Electron Transfer, Bios Scientific Publishers, Oxford, United Kingdom, ed. D. S. Bendall, p. 69-94, 1996.

 

62.              Northrup, S. H., Molecular Graphics and Simulation of Proteins and Nucleic Acids, in What Every Chemist Should Know About Computers, ACS Books, ed. T. J. Zielinski, in press, 1996.

 

63.              Northrup, S. H., Activation of an Enzyme Simulated by Explicit Dynamics of an Active Site Lid, Biophysical Journal, 71, p. 3, 1996.

 

64. Thomasson, K. A., I.V. Ouporov, T. Baumgartner, J. Czlapinski, T. Kaldor, and S. H. Northrup, Free Energy of Nonspecific Binding of Cro Repressor Protein to DNA, J. Phys. Chem B., 101, p. 9127-9136, 1997

 

65. Castro, G., C. A. Boswell, and S. H. Northrup, "Dynamics of Protein-Protein Docking: cytc and ccp revisited", J. Biomolec. Struct. and Dynamics; 16, p. 413, 1998.

 

 

M.S. Theses Directed

 

Guoyuan Liu, M.S. Thesis, A Simple Model of Protein Diffusion and Binding to DNA, May, 2002.

Sundari K. Rallapalli, M.S. Thesis, Brownian Simulation of Kinetics of Hemoglobin Assembly, August, 2001.

Kiran K. Mukhyala, M.S. Thesis, Kinetics of Alpha-Beta Assembly of Human Hemoglobin, May 2000.

Gabriel Castro, M.S. Thesis, Theoretical Studies of Protein-Protein Docking and Electron Transfer Reaction, August, 1998.

Sedonia Andrew, M.S. Thesis, Electron Transfer in Metalloproteins, May, 1994.

Cynthia Miller, M.S. Thesis, Electrostatic Analysis of Protein-Protein Complexes, May, 1991.

Robert G. Herbert, M.S. Thesis, Brownian Simulation of Protein Association and Reaction, May, 1990.

John C. L. Reynolds, M.S. Thesis, Computational Studies of Carbonic Anhydrase B, June, 1989.

Jeffrey O. Boles, M.S. Thesis, Computational Studies of Heme Proteins, June, 1988.

Jen Mann Kao, M.S. Thesis, Theory of Helix-Coil Transitions in Polypeptides, August, 1983.

 

Presentations

 

American Chemical Society, Southeast Regional Meeting, Knoxville, TN, Oct. 1999; talk entitled Computer Simulation of Protein-Protein Docking and Electrostatics.

American Chemical Society, Southeast Regional Meeting, Knoxville, TN, Oct. 1999; talk entitled Interactive Visualization of Orbitals Using Electron Dot Density Maps.

Murray State University, Department of Chemistry, Invited seminar, October 2000.

University of Memphis, Department of Chemistry, Invited seminar, February 2000.

North Dakota EPSCoR Conference on Protein-Protein Interactions, Grand Forks, ND; May, 1998.

      Presentation ≠ Computational Studies of Protein-Protein Association and Reaction.

American Chemical Society, 215th National Meeting, Dallas, TX; April, 1998.

Presentation ≠ Electron Transfer Rates Between Cytochrome c and Charged Metal-ion Complexes.

University of British Columbia, Department of Biochemistry and Molecular Biology, Vancouver, BC Canada; December 1997.

Presentation: :Electron Transfer in Metalloproteins.

Western Kentucky University, Department of Chemistry, Bowling Green, KY; August, 1997.

Presentation ≠ Electron Transfer in Metalloproteins.

University of Georgia, BMB Spring Symposium: Experimental and Computational Approaches to Structure, Athens, GA; April, 1996.

      Invited seminars - #1 What Every Chemist Should Know About Computational Biochemistry and #2 Computational Studies of Electron Transfer in Metalloproteins.

University of Tennessee, Knoxville, TN; February, 1996.

      Invited seminar - Computer Simulation of Motion of Proteins and Nucleic Acids.

University of Illinois, Champagne-Urbana, IL; October, 1995.

      Invited seminar - Computer Simulation of Interprotein Association and Electron Transfer.

Biophysical Society, 39th Annual National Meeting, San Francisco, CA; February, 1995.

      Presentation - Simulated Proton Uptake in Complex Formation Between Cytochrome c and Cytochrome b5.

American Chemical Society, 207th National Meeting, San Diego, CA; April, 1994.

      Presentation - Brownian Dynamics Simulation of Nonspecific Binding of Cro Repressor Protein to DNA. (undergraduate symposium)

American Chemical Society, 207th National Meeting, San Diego, CA; April, 1994.

      Presentation - Barrier to Rotation of Hydrobiaryl Radicals: a Computational Study. (undergraduate symposium)

Biophysical Society, 38th Annual National Meeting, New Orleans, LA; March, 1994.

      Presentation - Brownian Dynamics Simulation of Nonspecific Binding of Cro Repressor Protein to DNA.

 

University of South Alabama, Mobile, AL; December, 1993.

      Invited seminar - Theoretical Study of Protein-Protein Interactions.

Northern Illinois University, DeKalb, IL; April, 1993.

      Invited seminar - Electron Transfer in Metalloproteins.

University of Tennessee, Knoxville, TN; April, 1993.

      Invited seminar - Computer Simulation of Protein-Protein Interactions.

      Special Topics seminar - Protein Dynamics.

East Tennessee State University, Johnson City, TN; April, 1993.

      Invited seminar - Computer Simulation of Protein-Protein Interactions.

American Chemical Society, 205th National Meeting, Denver, CO; March, 1993.

      Invited lecture - Electron Transfer in Metalloproteins.

Biophysical Society, 37th Annual National Meeting, Washington, D.C.; February, 1993.

      Presentation - Simulation of Electron Transfer Self-Exchange in Cytochromes c and b5.

American Chemical Society, Nashville Section Meeting, Cookeville, TN; November, 1992.

      Invited lecture - Theoretical Simulation of Protein-Protein Interactions.

Marshall University, Department of Chemistry, Huntington, WV; October, 1992.

      Invited seminar - Theoretical Simulation of Protein-Protein Interactions.

Biophysical Society, 36th Annual National Meeting, Houston, TX; February, 1992.

      Presentation - Electrostatic Calculations of 2:1 Complexes of Cytochrome c and Cytochrome c Peroxidase.

NIH BBCA Study Section Grant Review team, Washington, D.C.; October, 1991.

Biophysical Society, 35th Annual National Meeting, San Francisco, CA; February, 1991.

      Presentation - Electrostatic Analysis of Docked Complexes of Cytochrome c and Cytochrome b5 Mutants.

NIH BBCA Study Section Grant Review team, Washington, D.C.; June, 1990.

Sanibel Symposium, St. Augustine, FL; March, 1990.

      Invited lecture - Brownian Simulation of Protein Association and Reaction.

Biophysical Society, 34th Annual National Meeting, Baltimore, MD; February, 1990.

      Presentations - Diffusional Association Dynamics of Proteins; Overcoming the Strict Steric Requirement and Electron Transfer Between Ferricytochrome c and Ferrocytochrome b5; Diffusion Theory and Experiment.

NIH BBCA Study Section Grant Review team, Washington, D.C.; October, 1989.

University of Houston, Chemistry Department, Houston, TX; March, 1989.

      Invited lecture - Theoretical Studies of Biomolecular Complex Formation.

Biophysical Society, 33rd Annual National Meeting, Cincinnati, OH; February, 1989.

      Invited lecture (at Molecular Biophysics Subgroup) - Electrostatics and Brownian Dynamics of Cytochrome Protein Encounters.

Tennessee Academy of Sciences, 98th Annual Meeting, Cookeville, TN; November, 1988.

      Lecture - Brownian Dynamics of Protein Association.

 

 

American Chemical Society, 40th Southeast Regional Meeting, Atlanta, GA; November, 1988.

      Invited lecture - Brownian Dynamics and Electrostatics of Association of Heme Proteins.

Mt. Sinai School of Medicine, City University of New York, New York, NY; October, 1988.

      Invited lecture - Brownian Dynamics and Electrostatics of Association of Heme Proteins.

DuPont Experimental Station, Wilmington, DE; June, 1988, as visiting scientist and consultant in the laboratory of Dr. James Matthew.

NIH BBCA Study Section Grant Review team, Washington, D.C.; June, 1988.

Georgia State University, Chemistry Department, Atlanta, GA; April, 1988.

      Invited Lecture - Brownian Dynamics and Electrostatics of Association of Heme Proteins.

Biophysical Society, 32nd Annual National Meeting, Phoenix, AZ; February, 1988.

NIH Physiology Study Section Grant Review Consultant, February, 1988.

DuPont Experimental Station, Wilmington, DE; invited lecturer in the Division of Central Research Molecular Biology Section, November, 1987.

      Title of talk - Brownian Dynamics of Protein Association.

1st Annual Minnesota Conference on Supercomputing in Chemistry and Biology, September, 1987.

      Title of talk - Brownian Dynamics Simulation of Protein Association.

American Chemical Society, 193rd National Meeting, Denver, CO; April, 1987.

      Title of paper - Diffusion Controlled Association Rate of Cytochrome c and Cytochrome c Peroxidase in a Detailed Topographical Model.

American Chemical Society, 192nd National Meeting, Anaheim, CA; September, 1986.

      Title of paper - Brownian Dynamics Simulation of Diffusion-Influenced Electron Transfer Reactions of Cytochromes.

Biophysical Society, 30th National Meeting, San Francisco, CA; February, 1986.

      Title of paper - Electrostatic Influences in Diffusion-Influenced Reactions of Biomolecules.

Biophysical Discussions, 5th Annual Meeting, Arlie, VA; November, 1985.

      Title of paper - Simulation of Biomolecular Diffusion and Complex Formation.

American Chemical Society, 33rd Southwest/37th Southeast Regional Meeting, Memphis, TN; October, 1985.

      Title of talk - Molecular Dynamics Simulation of Lipid Monolayers.

Sigma Pi Sigma, Honorary Physics Fraternity of TTU, banquet speaker, May, 1984.

Sigma Xi Scientific Research Society at TTU, Guest Luncheon Speaker, Fall, 1982.

Gordon Conference on Biopolymers, Holderness School, Plymouth, NH; July, 1982.

      Title of paper - Gated Diffusion-Influenced Ligand Binding to Proteins.

American Chemical Society, 179th National Meeting, Houston, TX; March, 1980.

      Title of paper - Molecular Dynamics of Ferrocytochrome c.

American Chemical Society, 35th Southwest Regional Meeting, University of Texas at Austin, TX; December, 1979.

      Title of talk - Simulation Studies of Diffusional Activated Processes.

 

Graduate Courses Taught in Last Five Years

 

Chem6320 ≠ Advanced Physical Chemistry, years ???

EVSC7910 ≠ Research Design in Environmental Chemistry; grant writing; 2 guest lectures.